Background: Ayurvedic scriptures extensively chronicle the use of honey by individuals with metabolic dysfunctions, including Madhumeha (Diabetes mellitus) and Ati-Sthulata (Obesity). Oral administration of honey for weight loss, with hypoglycemic and hypolipidemic qualities which aid in lowering Pitta, Kapha and Medas is good in managing metabolic health and promoting longevity. Aim/Objectives: The present study is a small attempt to understand the biomedical properties of honey obtained from an indigenous bee, Apis cerana indica. Materials and Methods: The bio-activity of honey is evaluated using standard procedure through in vitro enzyme inhibition assays of carbohydrate degrading enzyme spectrophotometrically. Results and Discussion: The potency of honey to suppress the enzymes that breaks down carbohydrates such as α-amylase and α-glucosidase, for regulating postprandial glucose spikes. Additionally, honey's metabolic effect manages Pitta,, which is commonly associated with Madhumeha. This research finding supports the use of honey in moderation as a natural remedy for holistic diabetes care. Conclusion: Biomedical potential of honey depends on the bioavailability of the bioactive compounds and on their methods of absorption and metabolization.
