New Hg (II) Complex: As a Novel, Green and Efficient Reusable Catalyst for Synthesis of Polyhydroquinolines via Hantzsch Condensation

Hengameh Deldar Ghasemi; SadeghAllameh; Safar Ali Beyramabadi; Hossein Behmadi; Ali Morsali

Asian Journal of Biological and Life Sciences,2018,7,1,17-20.

Published:April 2018

Type:Research Article

Authors:

Author(s) affiliations:

Hengameh Deldar Ghasemi¹, SadeghAllameh^2,*, Safar Ali Beyramabadi³, Hossein Behmadi⁴, Ali Morsali⁵

¹PhD student of chemistry, Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IRAN.

² Assistant Professor, Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IRAN.

³Associate Professor, Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IRAN .

⁴Assistant Professor, Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IRAN .

⁵Associate Professor, Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IRAN .

Abstract:

A novel Hg (II) complex based on 5-nitro-N1-((pyridin-2-yl) methylene) benzene-1,2-diamine (HgL₂) has been studied for catalytic performance in the synthesis of polyhydroquinoline derivatives. This efficient and eco-friendly catalyst has been utilized in a one-pot four-component Hantzsch condensation of dimedone, aromatic aldehydes, ethyl acetoacetate and ammonium acetate under solvent and free-solvent conditions. Mild reaction conditions, simple work-up procedure, being environmentally friendly and high product yields are advantageous feature of this method

Keywords:Aromatic aldehyde, Hantzschcondensation, Hg(II) complex, Polyhydroquinoline