Aim: The goal of this research was to evaluate the severity of foot ulcers in patients visiting the tertiary care facilities of Khammam region. Materials and Methods: The research design implemented a retrospective cross-sectional method to study for 6 months starting from August 2024 until January 2025 with a sample size of 235 patients. The study obtained data through medical records together with clinical assessment results. Results: We have analyzed how infection severity is affected by major risk elements involving age, smoking patterns, alcohol use, SES, alongside diabetic complications including glycemic control. Patients who had diabetes on its own or had diabetes combined with cardiovascular diseases developed more significant foot ulcers than those without such health conditions. Conclusion: Results from the study prove that integrating diabetes and comorbidity management approaches remains essential to reduce the foot ulcer revalence in patients.