Therapeutic Potential of Citrus Flavonoid Naringin in Management of Osteoporosis: Current Status and Future Perspectives

Asian Journal of Biological and Life Sciences,2021,10,3,527-532.
Type: Review Article
Author(s) affiliations:

Mukesh Yadav1,*, Nirmala Sehrawat1, Sunil Kumar1, Anil Kumar Sharma1, Nipunjot Kaur2, Amandeep Singh1,2, Rachna Nara1, Sachin Kumar3

1Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, INDIA.

2G.S.S.D.G.S. Khalsa College, Patiala, Punjab, INDIA.

3Department of Bioinformatics, Janta Vedic College, Baraut-Baghpat, Uttar Pradesh, INDIA.


Naringin is a plant based natural compound abundantly present in citrus fruits. Naringin has been reported for its vast range of therapeutic properties and it has been recognized as molecule of interest in treatment of various diseases. Naringin has been also investigated for its role in promoting bone development and maintenance. It has been found to promote bone formation and inhibit the bone resorption. It seems to be a potent candidate in treatment of osteoporosis. Osteoporosis is characterized by low bone mass and destruction of bone microstructure. Osteoporosis increases the risk of bone fracture. Naringin has been found effective in treatment of osteoporosis and improvement of bone health including bone mineral density and mechanical strength. In current review, the potential of naringin in treatment of osteoporosis has been reviewed. This article will provide important and concise information on therapeutic potential of naringin against osteoporosis.