Error message

Deprecated function: The each() function is deprecated. This message will be suppressed on further calls in theme_biblio_custom() (line 367 of /home/ajbls/public_html/sites/all/modules/biblio/includes/biblio_theme.inc).

Incidental Detection of HbQ-India during Beta-Thalassemia Screening

Asian Journal of Biological and Life Sciences ,2015,4,1,20-25.
Published:April 2015
Type:Research Article
Authors:
Author(s) affiliations:

Sandhya Iyer*, Suhas Sakhare, Caesar Sengupta, A. Velumani

Hematology Division, Thyrocare Technologies Limited, Plot No.D37/1,TTC Industrial area, MIDC, Turbhe, Navi Mumbai - 400703, INIDA.

Abstract:

HbQ-India is a relatively rare hemoglobin variant seen particularly in the Indian subcontinent. In this report we present twenty cases of HbQ-India variant and two cases of HbQ India/Beta- Thalassemia detected in our lab during thalassemia screening tests conducted in camps along with family studies of few cases. These cases were detected over a span of three months from samples screened for thalassemia. In order to perform familial studies, sample of family members of six cases were collected totaling to twenty-two affected cases. Molecular confirmation of the detected HbQ-India trait was done using PCR-ARMS technology. Our study detected frequency of HbQ-India carriers at 1.47%.